Dr. Zhang received his Ph.D degree from South China Normal University in 2016. His research interests focus on the molecular mechanism of mitochondrial dynamics in neurological diseases.
Email：keaixiaozhen@126.com; 20200133@m.scnu.edu.cn
Education and Academic Training
2020/09-now Research Fellow, Institute for Brain Research and Rehabilitation, South China Normal University, Guangzhou, China
2016.7-2019.7 assistant research fellow, Institute of Human Virology, Key Laboratory of Tropical Diseases Control Ministry of Education, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China
2008.9 - 2016.7 Ph.D. MOE Key Laboratory of Laser Life Science and Institute of Laser Life Science,
College of Biophotonics, South China Normal University
2003.9 - 2007.6 B.S. School of Life Science, Henan University
Funding
2018-2020 National Natural Science Foundation of China ($35,000 total costs)
Project: Studies on the molecular mechanisms underlying abnormal mitochondrial fusion/fission in neuronal cells during ZIKV infection
Role on project: PI
Recent publications（#first author；*corresponding author）
1. Jiawei Hao; Jinqian Li; Zhenzhen Zhang; Yang Yang; Qing Zhou; Tiantian Wu; Tongling Chen; Zhongdao Wu; Ping Zhang; Jun Cui; Yi-Ping Li ; NLRC5 restricts dengue virus infection by promoting the autophagic degradation of viral NS3 through E3 ligase CUL2 (cullin 2), Autophagy, 2022, 1-16
2.Liang Rong; Ni Li; Zhenzhen Zhang* ; Emerging therapies for glioblastoma: current state and future directions, Journal of Experimental & Clinical Cancer Research, 2022, 41(1): 1- 18
3. Zhenzhen Zhang#, Liang Rong, Yi-Ping Li*. Flaviviridae Viruses and Oxidative Stress：Implications for Viral Pathogenesis. Oxidative Medicine and Cellular Longevity. 2019:1409582
4. Zhenzhen Zhang#, Lei Liu, Xiaoxiao Jiang, Shaodong Zhai, Da Xing*. The essential role of Drp1 and its regulation by SNO-Parkin in dopaminergic neurodegeneration: implications for Parkinson’s disease. Antioxidants & Redox Signaling. 2016, 25(11): 609-622.
5. Zhenzhen Zhang#, Lei Liu, Shengnan Wu, Da Xing*. Drp1, Mff, Fis1, and MiD51 are coordinated to mediate mitochondrial fission during UV irradiation–induced apoptosis. FASEB J. 2016, 30(1): 466-476.
6. Yanyan Zheng#, Qingxiang Liu#, Yaoxing Wu#, Ling Ma, ZhenzhenZhang, Tao Liu, Shouheng Jin, Yuanchu She, Yi-Ping Li*, Jun Cui*. Zika virus elicits inflammation to evade antiviral response by cleaving cGAS via NS1-caspase-1 axis. The EMBO journal. 2018 37.
7. Yiyi Chen#, Ting Liu, Zhenzhen Zhang, Mingxiao Chen, Liang Rong, Ling Ma, Bolan Yu, De Wu, Ping Zhang, Xun Zhu, Xi Huang, Hui Zhang, Yi-Ping Li*. Novel genetically stable infectious clone for a Zika virus clinical isolate and identification of RNA elements essential for virus production. Virus research. 2018, 257: 14-24.