Yanmei Liu, M.D. Ph.D
Principal Investigator,
Laboratory of Developmental and Regenerative Medicine
Institute of Brain Research and Rehabilitation,
South China Normal University，
55 Zhongshan Avenue West, Tianhe District, Guangzhou,
Guangdong Province, China, 510631
E-mail: yanmeiliu@m.scnu.edu.cn
Dr. Yanmei Liu received her M.D. from the medical school of Peking University, her Ph.D. in Biology from National University of Singapore. She then obtained her postdoctoral training in the medical school of Dresden University of Technology in Germany. She joined the faculty as an Associate Investigator at the Institute of Molecular Medicine, Peking University from 2013 to 2018. Since September 2018, she has been a Principal Investigator at the Institute of Brain Research and Rehabilitation, South China Normal University. Her research interests include pancreatic beta cell development and regeneration, mechanism and therapy study of Early-onset epileptic encephalopathies.
Selected Publications：
1. Kang F, Zhou M, Huang X, Fan J, Wei L, Boulanger J, Liu Z, Salamero J, Liu Y*, Chen L*. E-syt1 Re-arranges STIM1 Clusters to Stabilize Ring-shaped ER-PM Contact Sites and Accelerate Ca2+ Store Replenishment. Sci Rep. 2019; 9: 3975. doi: 10.1038/s41598-019-40331-0.
2. Zhao J, Zong W, Zhao Y, Gou D, Liang S, Shen J, Wu Y, Zheng X, Wu R, Wang X, Niu F, Wang A, Zhang Y, Xiong JW, Chen L*, Liu Y*. In Vivo imaging of b-cell function reveals glucose-mediated heterogeneity of b-cell functional development. Elife. 2019 Jan 29;8. pii: e41540. doi: 10.7554/eLife.41540.
Highlighted by a Research Highlight in Nature Reviews Endocrinology (https://www.nature.com/articles/s41574-019-0181-y).
3. Wang Y, Han C, Zhu W, Wu Z, Liu Y*, Chen L*. An optical method to evaluate both mass and functional competence of pancreatic alpha- and beta-cells. Journal of Cell Science. 2016;129(12):2462-71. doi: 10.1242/jcs.184523. (Cover story)
4. Yuan T, Liu L, Zhang Y, Wei L, Zhao S, Zheng X, Huang X, Boulanger J, Gueudry C, Lu J, Xie L, Du W, Zong W, Yang L, Salamero J, Liu Y*, Chen L*. Diacylglycerol guides the hopping of clathrin-coated pits along microtubules for exo-endocytosis coupling. Developmental Cell. 2015;35(1):120-30.
Previewed in the same issue of Dev Cell, and highlighted in the F1000Prime and also at the American Society of Cell Biology (ASCB) website.
5. Liu Y, Suckale J, Masjkur J, Magro MG, Steffen A, Anastassiadis K, Solimena M. Tamoxifen-independent recombination in the RIP-CreER mouse. PLoS One. 2010 Oct 22;5(10):e13533.
6. Liu Y, Mziaut H, Ivanova A, Solimena M.beta-Cells at the crossroads: choosing between insulin granule production and proliferation. Diabetes Obes Metab. 2009 Nov;11 Suppl 4:54-64.
7. Liu Y, Du L, Osato M, Teo EH, Qian F, Jin H, Zhen F, Xu J, Guo L, Huang H, Chen J, Geisler R, Jiang YJ, Peng J, Wen Z. The zebrafish udu gene encodes a novel nuclear factor and is essential for primitive erythroid cell development. Blood. 2007 Jul 1;110(1):99-106.
8. Zhang Y, Wang J, Xing S, Li L, Zhao S, Zhu W, Liang K, Liu Y, Chen L. Mitochondria determine the sequential propagation of the calcium macrodomains revealed by the super-resolution calcium lantern imaging. Sci China Life Sci. 2020 Apr 8. doi: 10.1007/s11427-019-1659-4.
9. Dong D, Huang X, Li L, Mao H, Mo Y, Zhang G, Zhang Z, Shen J, Liu W, Wu Z, Liu G, Liu Y, Yang H, Gong Q, Shi K, Chen L. Super-resolution fluorescence-assisted diffraction computational tomography reveals the three-dimensional landscape of the cellular organelle interactome. Light Sci Appl. 2020 Jan 28;9:11. doi: 10.1038/s41377-020-0249-4.
10. Huang X, Fan J, Li L, Liu H, Wu R, Wu Y, Wei L, Mao H, Lal A, Xi P, Tang L, Zhang Y, Liu Y, Tan S*, Chen L*. Fast, long-term, super-resolution imaging with Hessian structured illumination microscopy. Nature Biotechnology. 2018; 36(5):451-459. doi: 10.1038/nbt.4115.
11. Ivanova A, Kalaidzidis Y, Dirkx R, Sarov M, Gerlach M, Schroth-Diez B, Müller A, Liu Y, Andree C, Mulligan B, Münster C, Kurth T, Bickle M, Speier S, Anastassiadis K, Solimena M. Age-dependent labeling and imaging of insulin secretory granules. Diabetes. 2013 Nov;62(11):3687-96.
12. Du L, Xu J, Li X, Ma N, Liu Y, Peng J, Osato M, Zhang W, Wen Z. Rumba and Haus3 are essential factors for the maintenance of hematopoietic stem/progenitor cells during zebrafish hematopoiesis. Development. 2011 Feb;138(4):619-29.